What does instrumentation refer to in the context of internal validity?

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Instrumentation, in the context of internal validity, specifically refers to changes or alterations made to the measurement tools or methods used during a study that may impact the reliability or accuracy of the data collection process. When a researcher uses different tools at different points in time or alters the way measurements are taken, it can introduce variability that affects the outcomes of the study. This means that any observed effects may not be solely due to the intervention or treatment being studied, but rather due to inconsistencies in how the outcomes are measured.

For instance, if a study originally employs a specific survey to gauge participants' responses but then switches to a different version of that survey midway through, the results may be skewed. Such changes can lead to questions about the validity of the conclusions drawn from the research, as the measure employed may not consistently assess the same attributes across all points of the study.

The other options address different aspects of research validity but do not specifically relate to instrumentation. Loss of subjects refers to attrition, which can affect representativeness but doesn't relate to how outcomes are measured. Homogeneity of subject characteristics pertains to the uniformity of the study population, affecting generalizability rather than the measurements themselves. Random sampling techniques concern how participants are selected for a study,

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